Open access
Aug 2026
miR-6615-3p-androgen receptor axis modulates granulosa cell fate via the MDM2-p53-BCL2 pathway in hen Prehierarchical follicles
Results suggest that miR-6615-3p downregulates AR and is associated with reduced MDM2 expression, enhanced p53 activation, and decreased BCL2 expression, indicating that it may regulate cell fate and steroid hormone synthesis, at least in part, through the MDM2-p53-BCL2 signaling pathway.
Di-Kai Zhang, Zhi-Chao Xu, Yuan-Yuan Zhou et al.
· Poultry Science · 0 citations