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Di-Wei Zheng

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Open access Jul 2026

SPgen: Proteome-wide Spatial Proteomics generation using multi-modality foundation models

SPgen integrates protein sequences, functional annotations, transcriptomic profiles, and spatial information to learn transferable representations that enable inference beyond experimentally profiled proteins, and accurately reconstructs measured spatial patterns, reduces measurement noise, and enables proteome-wide sp...

Jia-Chen Li, Kai-Yuan Yang, Qiaoling Che et al. · 0 citations

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