Open access
Sep 2026
MCM10, regulated by METTL3/ YTHDF1-mediated m6A modification, contributes to colorectal cancer progression through induction of M2 macrophage polarization
MCM10 is aberrantly overexpressed in CRC and linked to worse clinical outcomes and its oncogenic effects involve METTL3/YTHDF1-mediated mRNA stabilization and enhanced M2 macrophage polarization, suggesting a potential role in immune microenvironment modulation.
Qiao Qu, Zhilong Li, Da-Lu Wang et al.
· Cellular and Molecular Life... · 0 citations