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Open access Sep 2026

Single cell multi-omics guided hydrogel enables closed-loop therapy for renal osteodystrophy

Fracture repair in renal osteodystrophy remains challenging because impaired bone quality compromises fixation stability, while current systemic therapies regulating bone metabolism do not sufficiently address the disease-specific mechanisms underlying defective repair. An integrated strategy combining early fracture s...

Lei Fan, Ke-Nan Sun, Fei-Ping Xia et al. · 0 citations

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