Open access
Sep 2026
Switching apo- and holo-IscR control of LcrF alters how iron and oxygen regulate Yersinia virulence factors
The lcrFpType1 mutant lcrFpType1 mutant experienced altered colonization bottleneck and dissemination patterns compared to WT Yersinia, suggesting that expressing LcrF and T3SS genes in response to [2Fe-2S]-IscR rather than apo-IscR may alter infection dynamics.
Mané Ohanyan, G. I. Balazs, Karthik Hullahalli et al.
· Infection and Immunity · 0 citations