Die Zhang

Neuromelanin-sensitive magnetic resonance imaging in the diagnosis and assessment of Parkinson’s disease

Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized primarily by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc); noradrenergic neurons in the locus coeruleus (LC) are also frequently affected. Because clinical motor symptoms usually emerge only a...