Ketoanalogues of Essential Amino Acids in Chronic Kidney Disease: From Biochemical Rationale to Conditions for Clinical Effectiveness
Protein restriction is an established nutritional intervention for selected adults with non-dialysis chronic kidney disease (CKD); a supplemented very-low-protein diet (sVLPD) combines marked protein restriction with essential amino acids and their nitrogen-free keto- and hydroxyanalogues (KAs). KAs may accept amino gr...