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Author

Dimitrios Patoulias

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Review Open access Aug 2026

Switching from Vitamin K Antagonists to Direct Oral Anticoagulants in Frail Elderly Patients with Atrial Fibrillation: Systematic Review and Meta-Analysis

Background: Frailty complicates anticoagulation management in older patients with atrial fibrillation (AF), particularly when long-term vitamin K antagonist (VKA) therapy is already established. Whether switching to a direct oral anticoagulant (DOAC) improves outcomes in this setting remains uncertain, and guideline re...

P. Karakasis, Ricardo Gómez-Huelgas, Stylianos Tzeis et al. · 0 citations
Case report Open access Aug 2026

Secondary Hemophagocytic Lymphohistiocytosis Triggered by Visceral Leishmaniasis Due to Leishmania infantum: A Case Report

Clinicians should maintain a high index of suspicion in patients presenting with prolonged fever, splenomegaly, cytopenia, and marked hyperferritinemia, particularly in endemic regions, particularly in endemic regions.

C. Velliou, A. Varouktsi, Iraklis Leonidis et al. · 0 citations
Review Open access Jul 2026

Chronic Kidney Disease-Associated Cardiomyopathy: Mechanisms and Therapeutic Strategies.

A better understanding of CKD-CM pathogenesis is likely to enable early intervention and prevention, with successful outcomes measured by reduced progression to severe cardiomyopathy and lower cardiovascular mortality in CKD.

Konstantinos Grigoriou, Vasileios Lamprou, Anastasios Chatzichidiroglou et al. · 0 citations

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