Open access
Aug 2026
Spatial dynamics of cancer-associated fibroblasts links fibroblastic differentiation to immune exclusion and tumor progression
It is shown that aCAFs, whose expression has been associated with poor prognosis, tend to localize at tumor boundaries, where proximity to tumor cells predicts increased expression of aCAF-associated genes.
Ling-Yi Cai, Tai-Hsien Ou Yang, Dimitris Anastassiou
· Frontiers in Immunology · 0 citations