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Author

Ding-I Yang

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Review Open access Aug 2026

Protein Kinase C-delta (PKCδ) in Neurodegeneration and Cerebral Ischemia: Molecular Mechanisms and Therapeutic Implications

Protein kinase C delta (PKCδ), a calcium-independent novel PKC isoform, is increasingly recognized as a compartmentalized regulator of stress signaling in the central nervous system. Through tyrosine phosphorylation, subcellular translocation, regulation of its expression, and caspase-3-dependent proteolytic activation...

Yi-Heng Hsieh, I-Yen Lee, You Lien et al. · 0 citations

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