Dini Attala Hefa Insyira

Chemical Profiling and In Silico Study of Russelia equisetifomis Major Phytochemicals as Potential Dual-Site Acetylcholinesterase Inhibitors in Alzheimer’s Disease

Tilianin is a promising dual-site AChE inhibitor candidate that may simultaneously improve cholinergic neurotransmission and reduce β-amyloid (Aβ) aggregation against AD, and further in vitro and in vivo validation studies are required to confirm its therapeutic potential.