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Diogo Haddad Santos

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Sep 2026

GLP-1 receptor agonism in Alzheimer's disease after EVOKE: From single hypothesis to stratified program.

The phase 3 EVOKE and EVOKE + trials of oral semaglutide in early Alzheimer's disease missed their primary endpoint and every cognitive or functional secondary endpoint. A recent article by Hölscher revisits extension-phase data and reports partial separation at later timepoints, attributing the failure to limited brai...

A. M. Pereira da Silva, Diogo Haddad Santos · 0 citations

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