Diogo Rasteiro

In silico prediction of the permeability of phytochemicals across the blood-brain barrier

The role of phytochemicals like xanthines, and (poly)phenols in neurodegenerative diseases has been highly established and explored. However, the mechanism of these molecules to cross the membranes reaching the blood and the brain has largely been understudied. In this work, we used in silico methods to pred...