Review
Open access
Jul 2026
Cancer stem cells and drug resistance in cancer: molecular mechanisms and therapeutic targets
A comprehensive synthesis of the molecular and microenvironmental mechanisms underlying CSC-driven drug resistance is provided and emerging therapeutic strategies targeting CSC plasticity, niche interactions, metabolic adaptation, and immune evasion are critically discussed.
Hayam Hamdy, Youzhou Li, Chen Li et al.
· Molecular Biomedicine · 0 citations