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Domenico Maisano

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Open access Aug 2026

Decoding the causes of ischemic stroke despite ongoing oral anticoagulation and their clinical impact: the ASPERA-R study

Oral anticoagulants (OACs), including vitamin K antagonists and direct OACs, reduce stroke risk in atrial fibrillation (AF), yet breakthrough ischemic stroke still occurs in 1–2% of patients annually despite adequate therapy. The mechanisms underlying these events remain unclear. We aimed to identify potential causes o...

Federico De Santis, Matteo Foschi, Francesca Gabriele et al. · 0 citations

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