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Dong Chen

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Open access Aug 2026

Assessing microglial phagocytosis of apoptotic neurons in vitro: a multimodal approach

Microglia are the resident immune cells of the central nervous system, responsible for defending against infections, responding to tissue damage, and maintaining homeostasis. Dysregulation of their phagocytic activity has been implicated in many neurodegenerative diseases of the brain and the eye, including Alzheimer's...

A. Mukwaya, Zhuoran Yin, Ryan Yarcusko et al. · 0 citations
Review Jul 2026

Reprogramming Mammal Müller Glial Cells for Retinal Neuroregeneration.

Current knowledge of this integrated regulatory network, encompassing signaling pathways including Notch, Wnt/β-catenin, MAPK/ERK, PI3K/AKT, SMADs, and Hippo-YAP, alongside key transcription factors and epigenetic mechanisms, that collectively govern MG cell cycle reentry and neurogenesis in mammals are synthesized.

Lu Huang, Ethan Yao, Menglu Yang et al. · 1 citation

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