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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Dong Chen

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2 papers indexed here

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Oct 2026

Turn Shield into Sword: Pathological Hydroxyapatite-Targeting Micelles Drive Metabolic Stress-Induced Autophagy Dysfunction for Bone Metastasis Therapy

Bone metastasis remains a major clinical challenge in advanced breast cancer because therapeutic efficacy is limited by poor lesion targeting and systemic toxicity. Moreover, the hypoxic bone microenvironment induces protective autophagy in tumor cells, which maintains metabolic homeostasis and limits therapeutic eff...

Yun-Xia Ye, Rui-Lin Wang, Shi-Pei Nie et al. · 0 citations
Oct 2026

A biomimetic nanoplatform for targeted co-delivery of ABT-199 and ATRA potentiates acute myeloid leukemia therapy via DNA damage response suppression.

HPAA is established as a promising biomimetic nanoplatform for AML therapy by integrating active targeting with the novel drug repurposing of ATRA as a Chk1 suppressor to potentiate ABT-199 efficacy.

Zhi-Di He, Yu-Lin Xu, Zhi-Peng Tian et al. · 0 citations

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