Per- and polyfluoroalkyl substance (PFAS) exposures have been linked to reduced birth size, but the underlying epigenetic mechanisms remain unclear. Among 296 mother–infant dyads in the Atlanta African American Maternal–Child Cohort (2016–2020), early pregnancy maternal blood samples (8–14 weeks) were processed for s...
You-Ran Tan, Anne L. Dunlop, Todd M. Everson et al.· Environmental Science &...· 0 citations
Prenatal environmental exposures may influence fetal growth by disrupting the maternal metabolome and placental function. This exploratory study integrates untargeted maternal serum metabolomics and placental transcriptomics to identify shared molecular pathways through which the maternal environment affects fetal de...
Ye-Wei Wang, Dong-Hai Liang, Duan Wang et al.· Environment & Health· 0 citations
Mass Spectrometry Metabolomics Identification Connection Algorithm (MSMICA) is an algorithm for automated metabolite identification in untargeted liquid chromatography-high-resolution mass spectrometry (LC-HRMS) analyses. Limitations in metabolite identification can occur due to the availability and cost of standards a...
Jia-Da Zhan, J. Weinberg, William J. Crandall et al.· bioRxiv· 0 citations
Global analysis of the maternal lipidome during early pregnancy revealed diverse bioactive lipid involvement in the PFAS-SGA association and if antioxidants and anti-inflammatory nutrients would attenuate exposure effects on adverse maternal–child health outcomes.
K. Taibl, Anne L. Dunlop, Paula-Dene C. Nesbeth et al.· Environmental Health Perspec...· 0 citations
Overall, maternal dietary factors may influence susceptibility to PFAS-related fetal growth effects and may modify the inverse associations between prenatal PFAS exposure and birthweight for gestational age z-scores.
Yun-Jie Huang, Dong-Hai Liang, Anne L. Dunlop et al.· Nutrition and Health· 0 citations
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