Modified Bixuesan modulates inflammatory and apoptotic gene expression in post-radiotherapy chronic pharyngitis of laryngeal cancer: an integrative network pharmacology and in vitro validation study
Post-radiotherapy chronic pharyngitis affects 60%–80% of laryngeal cancer survivors and is characterized by sustained elevation of pro-inflammatory cytokines and dysregulation of key apoptotic and oncogenic signaling pathways, including NF-κB/PI3K-AKT/EGFR and TP53/CASP3 axes. Modified Bixuesan (MBS), a classical T...