Dong Yang

Multimodal neuroimaging changes and their behavioral, genetic, and neurotransmitter correlates in electroconvulsive therapy for major depressive disorder.

Findings suggest the left AG is a key region mediating ECT's effects, and indicates that ECT may exert its antidepressant action by modulating neurotransmitter systems, offering insights into the neural and molecular basis of its therapeutic efficacy in MDD.