This comprehensive review systematically summarizes high-quality literature published from 2020 to 2025, focusing on estrogen biosynthesis and metabolic dysregulation, dual genomic/non-genomic estrogen receptor signaling mediated by ERα, ERβ and GPER1, epigenetic regulatory networks, and bidirectional crosstalk between...
Jia-Xin Zhao, Donghai Li, Shao-Feng Yang et al.· Cancer Management and Resear...· 0 citations
This review critically evaluates the biological functions and clinical relevance of circRNAs, discusses the role of EV-derived circRNAs in metastasis monitoring, and outlines a roadmap to overcome current translational bottlenecks, ultimately assessing their potential as diagnostic, prognostic, and predictive tools in...
Xin Ma, Jing Du, Donghai Li· Cancer Control: Journal of t...· 0 citations
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