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Author

Donghai Li

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Review Open access Aug 2026

Recent Advances (2020–2025) in Estrogen and ER-Positive Breast Cancer: Receptor Signaling, Tumor Microenvironment, Endocrine Therapy Resistance and Innovative Treatment Strategies—A Comprehensive Review

This comprehensive review systematically summarizes high-quality literature published from 2020 to 2025, focusing on estrogen biosynthesis and metabolic dysregulation, dual genomic/non-genomic estrogen receptor signaling mediated by ERα, ERβ and GPER1, epigenetic regulatory networks, and bidirectional crosstalk between...

Jia-Xin Zhao, Donghai Li, Shao-Feng Yang et al. · 0 citations
Review Open access Aug 2026

Exploring the Clinical Transformation of circRNA as a Biomarker in Breast Cancer

This review critically evaluates the biological functions and clinical relevance of circRNAs, discusses the role of EV-derived circRNAs in metastasis monitoring, and outlines a roadmap to overcome current translational bottlenecks, ultimately assessing their potential as diagnostic, prognostic, and predictive tools in...

Xin Ma, Jing Du, Donghai Li · 0 citations

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