Cross-Linked Diselenide Nanovesicles against Acute Liver Injury by Seamless Integration of ROS Elimination and Source Inhibition.
This work introduces a cross-linked diselenide nanovesicles with surface folic acid modification (FA@cSeLAV), which effectively targets hepatic macrophages, key mediators of ROS-driven damage in ALI, and seamlessly integrates symptomatic-level ROS elimination with the inhibition of endogenous ROS production.