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Author

Dongryeol Ryu

2 papers indexed here

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Review Open access Sep 2026

Sarcopenia beyond muscle: endocrine–metabolic regulation and inter-tissue crosstalk across the muscle–tendon unit

Sarcopenia is characterized by a progressive loss of muscle strength and physical performance that frequently exceeds the decline predicted by muscle mass alone. This discrepancy indicates that functional deterioration is shaped not only by the force-generating capacity of skeletal muscle, but also by the tissues respo...

Guang Ta, Li Li, Cai Jing et al. · 0 citations
Review Open access Sep 2026

Mitochondrial Proteostasis Links Diabetes and Sarcopenia: Cross-Scale Convergence from Experimental Models to Human Multi-Omics

This review synthesizes evidence demonstrating how insulin resistance, hyperglycemia, lipotoxicity, and inflammation converge on skeletal muscle mitochondrial proteostasis to drive progressive decline in type 2 diabetes mellitus, and proposes a diabetes-centered framework where mitochondrial proteostasis failure mediat...

Shi-Bo Wei, Soyeon Shin, Dongryeol Ryu et al. · 0 citations

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