Dongyang Wu

Unraveling the association between triclosan and breast cancer: A multidimensional research strategy integrating machine learning, mendelian randomization, and molecular dynamics simulations.

Triclosan stably binds and suppresses NR3C1, removing NR3C1-dependent restraint on proliferation, colony formation, migration, and cell cycle progression, and provides a multi-level evidence chain from binding to prognosis, clarifying triclosan's pro-cancer mechanisms and offering clues for risk evaluation and interven...