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Douglas L. Feinstein

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Review Open access Aug 2026

The locus coeruleus at the crossroads of inflammation and neurodegeneration in multiple sclerosis

Multiple sclerosis (MS) is increasingly recognized as a systems-level disorder encompassing grey matter injury, network disconnection, and neuropsychiatric symptoms alongside demyelination. Within this framework, the locus coeruleus (LC), the principal source of noradrenaline (NA) in the central nervous system, emerges...

Intakhar Ahmad, Rebecca Alemani, Douglas L. Feinstein · 0 citations

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