Open access
May 2026
Spatial distribution of blood-brain barrier membrane proteins is controlled by sorting motifs and physiological signals in vivo
A method for measuring polarized protein sorting at the blood-brain barrier in vivo is established and a change in membrane protein distribution that aligns with circadian rhythms is observed, revealing an under-appreciated dimension of BBB dynamics.
J. Amick, Shamika Bhandarkar, Douglas R. Wilcox et al.
· bioRxiv · 2 citations