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Author

Drew Friedmann

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Open access Sep 2026

Topographic structure and function of locus coeruleus noradrenaline neurons.

Noradrenaline (also known as norepinephrine) is released throughout most of the central nervous system by neurons in the locus coeruleus1-4. Here we identified a relationship between the morphologies, gene expression and activity of noradrenergic neurons in locus coeruleus in mice. Axonal projections of individual neur...

Zhi-Xiao Su, P. Kosillo, Kanghoon Jung et al. · 0 citations
Open access Sep 2026

Architecture of the serotonergic projectome in the mouse brain.

The serotonin system innervates nearly the entire brain to support diverse functions, and its dysfunction is implicated in multiple psychiatric disorders. Although recent studies suggested that this anatomically diffuse system supports differentiated rather than uniform modulation, its overall organization is unclear....

Jun H. Song, Drew Friedmann, Yun-Ming Wu et al. · 1 citation
Open access Jul 2026

Projectomic Organization of the Serotonin System of the Mouse Brain

It is shown that the serotonin projectome is organized by functional relatedness rather than physical proximity of its targets, and projectomic identity emerges as a central axis linking axon collateralization, molecular diversity, and behavioral function.

Jun H. Song, Drew Friedmann, Yun-Ming Wu et al. · 0 citations

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