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Author

Duhyeong Hwang

2 papers indexed here

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Open access Sep 2026

Ritonavir-Loaded PEG-b-PCL Polymeric Micelles: Reduced Excipient Requirements and Comparable Oral Pharmacokinetics in Rats

Background: Ritonavir (RTV), an HIV-1 (human immunodeficiency virus-1) protease inhibitor, has low aqueous solubility and poor oral bioavailability, requiring large amounts of excipients that result in bulky dosage forms and poor patient compliance. We aimed to develop an RTV-loaded polymeric micelle formulation with h...

Eungyeop Lee, Jihoon Lee, So-Young Park et al. · 0 citations
Review Sep 2026

Integrating tumor microenvironment modulation with nanocarrier engineering for enhanced tumor-targeted delivery.

The tumor microenvironment (TME) imposes vascular, stromal, metabolic, and immune barriers that restrict nanoparticle (NP) extravasation, interstitial penetration, cellular access, and therapeutic activity in solid tumors. Because the dominant barrier and the delivery step most directly constrained vary across tumor ty...

Thu A. Hoang, Eunhee Lee, Duhyeong Hwang et al. · 0 citations

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