Duo-Duo Hu

Advances in Synthetic Methods for Chiral Trifluoromethylthiolated Compounds

Driven by its strong electron-withdrawing properties and high lipophilicity, the trifluoromethylthio (–SCF3) group has emerged as a privileged motif in bioactive small molecules, particularly in pharmaceutical and agrochemical development. However, the asymmetric synthesis of chiral –SCF3-containing compounds remains a...