Author

Duo Li

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Open access Jul 2026

The novel biguanide derivative 4C synergizes with talazoparib by inducing ferroptosis via the SREBP1/FASN/ SLC7A11/GPX4 axis in bladder cancer

It is demonstrated that the combination of 4C and talazoparib induces ferroptosis via the SREBP1/FASN axis, providing a promising novel combination therapeutic strategy for the treatment of BC.

Jia Yao, Weifan Wang, Duo Li et al. · Cell Death Discovery · 0 citations