Duraira Durairaj Ragu Varman

NOD-like receptor pyrin domain-containing protein 3 inflammasome activation in microbiota-induced neuroinflammation: Relevance to autism and stress disorders

Novel mechanistic findings that link gut microbiota dysregulation to NLRP3-mediated neuroinflammation are integrated, its involvement in ASD and stress susceptibility is clarified, and treatment approaches targeting microbial modulation and inflammasome suppression are examined.