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Author

Dustin E. Bosch

2 papers indexed here

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Open access Aug 2026

Targeting Circulating Fatty Acid Binding Protein 4 Ameliorates Obesity-Associated Hepatic Steatosis.

BACKGROUND & AIMS Obesity is a major driver of metabolic dysfunction-associated steatotic liver disease (MASLD), yet the molecular mechanisms linking excess adiposity to hepatocellular lipid accumulation remain incompletely defined. We investigated whether circulating fatty acid-binding protein 4 (FABP4) mediates adipo...

Xingshan Jiang, Anthony Avellino, Jianyu Yu et al. · 0 citations
Open access Aug 2026

Secreted nuclease effector neutralization by active site mimicry in Bacillota

A multivalent Tde/Tdi neutralization mechanism where an initial high-affinity interface increases the local concentration of Tdi’s P(Φ)4GG motif, enabling it to displace the Tde active site through structural mimicry, which may aid in eliminating the toxic effector.

Romina Abbasian, Bishal Parajuli, Liping Yu et al. · 0 citations

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