Author

Dylan Gill

2 papers indexed here

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Open access Sep 2026

Local and systemic immune responses during rhBMP-2 mediated bone regeneration are dose-dependent in rat model of critical-sized bone defect healing.

Bone morphogenetic proteins (BMPs) are among the most potent clinical therapeutics for promoting bone regeneration, yet their use is limited by potential adverse events such as heterotopic bone formation, osteolysis, and soft tissue inflammation. Sustained release delivery systems may reduce the minimum effective BMP d...

Lia K. Strait, Lucy Rose, Tyler Guyer et al. · Bone · 0 citations

Open access Jul 2026

Systemic administration of all-trans retinoic acid modulated circulating immune cells but failed to improve healing in a preclinical model of musculoskeletal trauma

The effects of ATRA on peripheral blood immune cells both in vitro and in vivo using a rodent model of bone and muscle trauma revealed that a specific subset of MDSCs were depleted by systemic ATRA administration, and healing overall was not altered by ATRA treatment.

Tyler Guyer, Dylan Gill, K. Leguineche et al. · Frontiers in Immunology · 0 citations