Author

E. Acar

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Open access Oct 2026

Synthesis, Characterization, and Anticancer Activity of Pyrene‐Based Schiff Base Ligands and Their Transition Metal Complexes

This study details the synthesis, characterization of unsymmetrical Schiff base ligand and their metal complexes Ni(II), Zn(II), Pb(II), and Cu(II) for anticancer assessment. These ligands were prepared by condensation reaction between 1,2‐phenylenediamine in combinations with 2,5‐dihydroxybenzaldehyde, 1‐pyrenecar...

Hilal Ay, O. Sahin, S. Karakurt et al. · ChemistrySelect · 0 citations

Sep 2026

Suppressing Liver Cancer via the VEGFR1 Receptor using De novo Ellagic Acid Derivatives and Co-drugs: Comprehensive In silico Biochemistry Research with ADMET, RMSD, Molecular Docking, and Molecular Dynamics Simulations.

INTRODUCTION Ellagic acid, Formononetin, and Glycitein are bioactive polyphenols possessing anticancer activity via apoptosis, cell cycle inhibition, and oncogenic signaling pathway modulation. In particular, Ellagic acid demonstrated interesting activity towards hepatocellular carcinoma (HCC), with the potential antia...

Soykan Ağar, E. Acar, Ozan Aldemir et al. · Current Topics in Medicinal... · 0 citations