Purpose: Enhancer of zeste homolog 2 (EZH2) is an epigenetic regulator implicated in the pathogenesis of diffuse large B-cell lymphoma, but the prognostic value of its protein expression is uncertain. We evaluated EZH2 expression and its associations with clinicopathological features and survival.Materials and Methods:...
Mehmet Mutlu Kıdı, Mehmet Turker, Sedat Biter et al.· Cukurova Medical Journal· 0 citations
Background/Objectives: The prognosis of metastatic rectal cancer remains poor, and few reliable prognostic biomarkers are available. DHX9 and CD47 have been implicated in colorectal cancer biology, but their prognostic value in metastatic disease remains unclear. We evaluated the associations of DHX9 and CD47 expressio...
Ş. Yaslıkaya, Ş. A. İpek, T. Toyran et al.· Medical Science· 0 citations
Background/Objectives: Immune checkpoint inhibitors have become a standard treatment option for advanced/metastatic non-small cell lung cancer (NSCLC); however, considerable heterogeneity exists among patients regarding treatment response and survival. This study aimed to determine whether the pretreatment modified Gla...
Sedat Biter, Mehmet Mutlu Kıdı, Yasemin Aydınalp Camadan et al.· Journal of Clinical Medicine· 0 citations
Aim: Leptomeningeal metastasis (LM) from breast cancer carries a poor prognosis, and most published cohorts originate from high-volume referral centers. We aimed to identify factors associated with overall survival (OS) after an LM diagnosis in routine practice and to describe diagnostic and treatment patterns.Methods:...
Mehmet Mutlu Kıdı, Omer Kaya, Sedat Biter et al.· Cukurova Anestezi ve Cerrahi...· 0 citations
These exploratory findings do not support the clinical use of EZH2 as a biomarker at this stage; prospective, multicenter studies using predefined thresholds and standardized immunohistochemical methods are needed to clarify its potential role as a marker complementary to PD-L1.
E. Asarkaya, Hatice Asoğlu, Abdurrahman Aykut et al.· Journal of Clinical Medicine· 0 citations
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