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Pediatric brain tumors—particularly pediatric low-grade gliomas (pLGG)—represent a major survivorship inequity between high-income countries (HICs) and low- and middle-income countries (LMICs). While pLGG is highly curable in optimal-resource settings, outcomes in LMICs remain suboptimal due to delays in diagnosis, lim...
PURPOSE OF REVIEW The fifth edition of the WHO Classification of Tumors of the Central Nervous System marked a paradigm shift from predominantly histopathological classification toward integrated molecular-pathological definitions. This review summarizes the contemporary molecular landscape of pediatric gliomas, pivota...
Virtual multidisciplinary tumor boards are a feasible and impactful model for improving pediatric neuro-oncology care in LMICs, as they can enhance diagnostic accuracy, facilitate evidence-based and consensus treatment decisions with local applicability, and strengthens clinician and institutional capacity.
Radiation-induced glioma of the pons is a rare and serious complication occurring in patients previously treated by RT for childhood craniopharyngioma and highlights the need for clinical vigilance and further research to prevent it.
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