Author

E. Chingizova

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Open access Aug 2026

Triterpene Glycosides from the Sea Cucumber Ocnus glacialis Display Cytotoxic and Colony-Inhibiting Activity Against Cancer Cells

As a result of investigation of glycosidic composition of the sea cucumber Ocnus glacialis (Cucumariidae, Dendrochirotida) two new glycosides, glacialisosides A (1) and B (2), were isolated. Their structures were established by in-depth analysis of 1H, 13C NMR, 1D TOCSY, and 2D NMR (1H,1H COSY, HMBC, HSQC, ROESY), in a...

A. Silchenko, E. Chingizova, E. Menchinskaya et al. · Marine Drugs · 0 citations

Open access Sep 2026

Trans-Vitisin B Targets Neuroinflammation, Oxidative Stress, and Tau Pathology to Improve Behavioral Outcomes in a Mouse Model of Parkinson’s Disease

Unlike L-DOPA’s direct dopaminergic stimulation, tVB’s neuroprotective efficacy is mediated through multilevel regulation of key PD pathogenetic pathways, including neuroinflammation, oxidative stress, and impaired proteostasis.

Evgeniy A. Pislyagin, I. Manzhulo, Irina Agafonova et al. · Antioxidants · 0 citations