Author

E. Costa

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Open access Sep 2026

Phytochemical Investigation and Cytotoxic Activity of Annona amazonica (Annonaceae): Comprehensive Spectroscopic Characterization of N-Formylactinodaphnine

Annona amazonica R. E. Fries (Annonaceae) is a tropical species native to Central and South America whose phytochemical profile remains poorly investigated. In the present study, the bark of A. amazonica was subjected to phytochemical investigation using conventional chromatographic techniques, leading to the isolation...

J. F. Auzier, Thayline Rayany Batista Menezes, Maria Lúcia Belém Pinheiro et al. · Molecules · 0 citations

Review Open access Jul 2026

Artificial Intelligence and Natural Photosensitizer-Based Nanopharmaceuticals in Photodynamic Therapy: Advanced Modeling, Data-Driven Optimization, and Translational Perspectives

Photodynamic therapy (PDT) is a minimally invasive therapeutic modality based on the interaction between a photosensitizer (PS), light, and molecular oxygen to generate reactive oxygen species (ROS) capable of inducing localized cytotoxicity. Natural products provide a chemically diverse source of photosensitizers, inc...

R. Gonçalves, E. Costa · Pharmaceutics · 0 citations

Review Open access Sep 2026

Hydrolates as Sustainable Phytochemical Resources for Nano-Enabled Strategies in Food Preservation, Active Packaging, and Sustainable Agriculture

Hydrolates are aqueous co-products of aromatic-plant distillation whose composition and functionality differ from those of the corresponding essential oils. This critical review links botanical source, distillation conditions, chemical composition, quantitative biological performance, food or agricultural application,...

R. Gonçalves, E. Costa · Applied Nano · 0 citations