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Author

E. De-Domenico

2 papers indexed here

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Open access Aug 2026

Microglia activation by derepression of endogenous retroviruses drives inflammation and cellular senescence

DAXX, a histone chaperone and RTE repressor, is downregulated during aging, preserves microglia homeostasis and inhibits cellular senescence, highlighting the importance of heterochromatin maintenance in preserving adult microglial identity and plasticity, with broader implications for brain homeostasis, healthy aging...

Xin Yan, Christina Georgopoulou, Hang-Mao Lee et al. · 1 citation
Open access Aug 2026

Memory T Cells in MHC-Deficient Humanized Mice

This work investigated how elimination of murine MHC together with different conditioning regimens shapes human T-cell maturation in vivo, and revealed marked differences in T-cell differentiation across models.

M. Darguzyte, Ж. Ш. Жумадилова, F. Khan et al. · 0 citations

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