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Open access Jul 2026

Neuroplasticity and immune system are related to altered grey matter networks: a cohort study in sporadic Alzheimer’s disease

Grey matter network topology is altered in Alzheimer’s disease and these alterations are related to cognitive decline, which suggests that preserving cognitive function in the presence of amyloid and prevention of dementia A+ may require therapies that strengthen synapses and targets the innate immune system in addition to tau.

Diederick M. de Leeuw, F. Duits, E. Dicks et al. · 0 citations