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Author

E. Ducas

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Open access Sep 2026

Identification of the Acetamide-Chalcone Derivative That Selectively Inhibits ABCG2 Transport Activity

Multidrug resistance (MDR) remains a major obstacle to effective cancer chemotherapy, often driven by the overexpression of ABC transporters such as ABCG2. In this study, we identified the synthetic chalcone derivative, B5, as a selective ABCG2 inhibitor. Among the 20 chalcone analogs evaluated, B5, bearing an acetamid...

Arthur Henrique Gomes de Oliveira, E. Ducas, Thales Kronenberger et al. · 0 citations

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