Serum hypoxia-inducible factors, heat shock proteins, and mitochondrial biomarkers in relation to neurocognitive performance in obstructive sleep apnea: a cross-sectional study.
STUDY OBJECTIVES Obstructive sleep apnea(OSA) is linked to impaired cognitive functions through a variety of underlying mechanisms. We investigated possible hypoxic, inflammatory and mitochondrial mediators of cognitive dysfunction in OSA. METHODS We prospectively enrolled 146 adult patients with OSA and 103 healthy...