Jul 2026
GSTT1 promotes stemness and FGFR inhibitor sensitivity in pancreatic cancer through regulation of CD133 (PROM1).
A GSTT1HighCD133High stem-like subpopulation in metastatic PDA is identified and an FGFR-dependent signaling axis that sustains this state is identified, representing a potential therapeutic vulnerability.
D. de la Caridad Delgado Herrera, Alejandro Arroyo Roman, Riyan N. Campbell et al.
· Cancer Letters · 0 citations