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Author

E. Fischer

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Aug 2026

Full-length premembrane protein is not required for mature Zika virus particle assembly.

Assembly of flaviviruses such as Zika virus (ZIKV), dengue virus, and West Nile virus in the host cell endoplasmic reticulum is driven by the structural envelope (E) and premembrane (prM) proteins. The formation of an infectious virion requires cleavage of prM by the host furin protease during a maturation step that is...

Kimberly A. Dowd, Michelle Schroeder, Egan Sanchez et al. · 0 citations

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