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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

E. Gorshkova

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Review Open access Jul 2026

Nef as a driver of immunodeficiency and HIV-associated diseases: insights from mouse models

This review summarizes existing transgenic mouse models with cell type-specific Nef expression and humanized mouse models used in HIV research, including models based on Nef-deficient strains, to provide experimental validation for the clinical implementation of Nef inhibitors in combination with established ART.

A. Yakovleva, E. Gorshkova, E. Gubernatorova et al. · 0 citations

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