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E. Guilherme

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Review Open access Aug 2026

INCLUSION BODIES IN RECOMBINANT PROTEIN PRODUCTION IN ESCHERICHIA COLI: FORMATION, RECOVERY, AND IMPLICATIONS FOR DOWNSTREAM PROCESSING

Recombinant protein production in Escherichia coli is a well-established biotechnology platform, but intense heterologous expression frequently results in inclusion bodies. These aggregates are not necessarily deposits of completely misfolded protein: they may retain native-like structural elements and, in selected sys...

Flávia Bruna Ribeiro Batista, B. M. A. de Carvalho Mesquita, Demerson Arruda Sanglard et al. · 0 citations

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