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E. H. Sadykov

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Open access Sep 2026

Synthesis, Z/E Isomerism, and Cytotoxic Activity of β-Hydroxy Oximes Derived from Indenoquinoxalinone, Tryptanthrin, and a Tricyclic Isatin Analogue: A Combined Experimental and DFT Study

Indolo[2,3-b]quinoxalines and their N-substituted derivatives exhibit anticancer activity. In this work, a convenient two-step protocol comprising base-promoted aldol condensation followed by oximation was used for the synthesis of novel β-hydroxy oximes from heterocyclic ketones. The oximes were obtained as Z/E mixtur...

A. V. Uvarov, E. Plotnikov, Daria D. Eskova et al. · 0 citations

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