PURPOSE
This prospective, randomized neoadjuvant study evaluated DNA-based biomarkers to identify breast cancer patients most likely to benefit from carboplatin (Cb). While Cb improves outcomes in triple-negative breast cancer (TNBC), responses vary, and its role in aggressive hormone receptor-positive breast cancer (H...
Arne V. Pladsen, M. L. Smebye, Øystein Garred et al.· Clinical Cancer Research· 0 citations
The gut microbiome has emerged as a promising source of biomarkers to enhance early detection of colorectal cancer (CRC). However, sex-specific differences in gut microbial profiles and their relationship to CRC risk remain underexplored. Our objective was to investigate sex-specific differences in gut microbial...
C. Bucher-Johannessen, A. S. Kværner, E. Birkeland et al.· Biology of Sex Differences· 1 citation
Some of the advantages of familial data using the Norwegian Mother, Father and Child Cohort Study (MoBa), a population-based cohort of parents and offspring with extensive genotype data, are illustrated along with broad and longitudinal phenotyping of health and functioning.
E. Corfield, A. Shadrin, O. Frei et al.· Nature· 3 citations
Analysis of a markedly larger, higher-coverage, and geographically diverse whole-genome sequencing dataset from 529 ancient individuals sheds important light on the demographic impact of major sociohistorical changes that occurred during the late Medieval period in Scandinavia and the Baltic region and link Christianis...
Xiaodong Liu, K. Moore, S. Ebenesersdóttir et al.· 0 citations
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