International case-control study of DNA methylation biomarkers for the minimally invasive diagnosis of esophageal squamous cell carcinoma.
BACKGROUND Esophageal squamous cell carcinoma (ESCC), the most common type of esophageal cancer worldwide, is usually diagnosed via esophagogastroduodenoscopy (EGD), an expensive procedure having limited availability in low- and Middle-Income countries (LMICs). We therefore developed diagnostic strategy that applies ES...