Nigrostriatal free-water imaging and volumetry outperform quantitative T1 in neurodegenerative Parkinson syndromes.
BACKGROUND The relative value of nigrostriatal volumetry, quantitative T1 relaxation, and multicompartment diffusion MRI in neurodegenerative Parkinson syndromes is unclear. OBJECTIVES To compare quantitative T1 relaxation and diffusion microstructure imaging-derived free fluid fraction (V-CSF) in the putamen and sub...